5/29/2025
Last update
5/29/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 6 Reviews
8.2
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Inositol
500 mg
**
Top Medical Research Studies
9
ITPP enhances heart attack recovery
We explored the potential of myo-inositol trispyrophosphate (ITPP) as a treatment for heart attacks and its effect on heart tissue injured by low oxygen levels. This research indicates ITPP modifies hemoglobin in red blood cells, enhancing the delivery of oxygen throughout the body.
Using an animal model for myocardial infarction, we observed that ITPP administration provided significant protection against heart failure and aided in recovery from left ventricular remodeling following the heart attack.
In our laboratory studies, heart muscle cells exposed to low oxygen levels reacted quickly to ITPP treatment, showing increased activity of a protein known as HIF-1. Interestingly, this overactivity was countered by ITPP when it was in the red blood cells, which suggests a strong connection between shear stress from blood flow and oxygen release facilitated by the modified hemoglobin.
Overall, the findings indicate that ITPP could be a game-changer in treating injuries to heart tissues related to low oxygen or ischemia. This approach may open new avenues for effectively managing damage caused by heart attacks.
Using an animal model for myocardial infarction, we observed that ITPP administration provided significant protection against heart failure and aided in recovery from left ventricular remodeling following the heart attack.
In our laboratory studies, heart muscle cells exposed to low oxygen levels reacted quickly to ITPP treatment, showing increased activity of a protein known as HIF-1. Interestingly, this overactivity was countered by ITPP when it was in the red blood cells, which suggests a strong connection between shear stress from blood flow and oxygen release facilitated by the modified hemoglobin.
Overall, the findings indicate that ITPP could be a game-changer in treating injuries to heart tissues related to low oxygen or ischemia. This approach may open new avenues for effectively managing damage caused by heart attacks.
Read More
Most Useful Reviews
9
Various benefits
1 people found this helpful
Inositol is beneficial for numerous conditions, from diabetic nerve pain to high cholesterol and even polycystic ovary syndrome. It's been shown to help balance chemicals, aiding conditions like panic disorders and potentially reducing the risk of heart attack through improved cholesterol levels.
Read More
9
Cholesterol reduction
16 people found this helpful
Great! Just 4 grams of inositol daily can lower triglycerides and "bad" cholesterol by 20-30%, thus reducing the risk of heart attack. It's vital for women, as the body produces three-quarters of its needs, with food supplying the rest. Studies indicate that additional inositol intake can help normalise hormonal balance in women.
Read More
7.5
Cholesterol improvement
1 people found this helpful
NOW Inositol 500 mg, previously known as B8, is a vitamin-like substance that the body synthesises from glucose. It's vital for several organs, especially relating to eye health. A shortage can lead to eye diseases. Inositol benefits heart health by contributing to normal cholesterol levels, which is crucial to prevent heart attack risk.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
- All Researches
9
ITPP enhances heart attack recovery
We explored the potential of myo-inositol trispyrophosphate (ITPP) as a treatment for heart attacks and its effect on heart tissue injured by low oxygen levels. This research indicates ITPP modifies hemoglobin in red blood cells, enhancing the delivery of oxygen throughout the body.
Using an animal model for myocardial infarction, we observed that ITPP administration provided significant protection against heart failure and aided in recovery from left ventricular remodeling following the heart attack.
In our laboratory studies, heart muscle cells exposed to low oxygen levels reacted quickly to ITPP treatment, showing increased activity of a protein known as HIF-1. Interestingly, this overactivity was countered by ITPP when it was in the red blood cells, which suggests a strong connection between shear stress from blood flow and oxygen release facilitated by the modified hemoglobin.
Overall, the findings indicate that ITPP could be a game-changer in treating injuries to heart tissues related to low oxygen or ischemia. This approach may open new avenues for effectively managing damage caused by heart attacks.
Using an animal model for myocardial infarction, we observed that ITPP administration provided significant protection against heart failure and aided in recovery from left ventricular remodeling following the heart attack.
In our laboratory studies, heart muscle cells exposed to low oxygen levels reacted quickly to ITPP treatment, showing increased activity of a protein known as HIF-1. Interestingly, this overactivity was countered by ITPP when it was in the red blood cells, which suggests a strong connection between shear stress from blood flow and oxygen release facilitated by the modified hemoglobin.
Overall, the findings indicate that ITPP could be a game-changer in treating injuries to heart tissues related to low oxygen or ischemia. This approach may open new avenues for effectively managing damage caused by heart attacks.
Read More
User Reviews
USERS' SCORE
Good
Based on 6 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Various benefits
1 people found this helpful
Inositol is beneficial for numerous conditions, from diabetic nerve pain to high cholesterol and even polycystic ovary syndrome. It's been shown to help balance chemicals, aiding conditions like panic disorders and potentially reducing the risk of heart attack through improved cholesterol levels.
Read More
9
Cholesterol reduction
16 people found this helpful
Great! Just 4 grams of inositol daily can lower triglycerides and "bad" cholesterol by 20-30%, thus reducing the risk of heart attack. It's vital for women, as the body produces three-quarters of its needs, with food supplying the rest. Studies indicate that additional inositol intake can help normalise hormonal balance in women.
Read More
7.5
Cholesterol improvement
1 people found this helpful
NOW Inositol 500 mg, previously known as B8, is a vitamin-like substance that the body synthesises from glucose. It's vital for several organs, especially relating to eye health. A shortage can lead to eye diseases. Inositol benefits heart health by contributing to normal cholesterol levels, which is crucial to prevent heart attack risk.
Read More
7.5
Reduces heart risk
1 people found this helpful
The quality, ingredients, size and packaging are superb🤩🤩🤩. Inositol, known as the "vitamin of youth", regulates fat metabolism, decreases cholesterol levels, and reduces the risk of heart attack, atherosclerosis, and obesity. It also stabilises blood sugar levels, curbing appetite and potentially preventing hunger attacks.
Read More
7.5
Hormonal balance
1 people found this helpful
Just 4 grams of inositol per day can lower triglycerides and "bad" cholesterol by 20-30%, thereby decreasing the risk of heart attack. For women, it’s essential as the body produces three quarters of its needs. Additional dietary inositol aids in normalising hormonal balance.
Read More
Frequently Asked Questions
9
Cholesterol reduction
16 people found this helpful
Great! Just 4 grams of inositol daily can lower triglycerides and "bad" cholesterol by 20-30%, thus reducing the risk of heart attack. It's vital for women, as the body produces three-quarters of its needs, with food supplying the rest. Studies indicate that additional inositol intake can help normalise hormonal balance in women.
7.5
Hormonal balance
1 people found this helpful
Just 4 grams of inositol per day can lower triglycerides and "bad" cholesterol by 20-30%, thereby decreasing the risk of heart attack. For women, it’s essential as the body produces three quarters of its needs. Additional dietary inositol aids in normalising hormonal balance.
2
Heart palpitations
I started with 1 capsule daily, but developed heart palpitations when lying down and generally felt unwell. Quitting caused severe acne, so I resumed in smaller doses. The benefits for my PCOS seem minimal compared to iodine supplements. I recommend trying the powder form for control over dosage.
7.5
Reduces heart risk
1 people found this helpful
The quality, ingredients, size and packaging are superb🤩🤩🤩. Inositol, known as the "vitamin of youth", regulates fat metabolism, decreases cholesterol levels, and reduces the risk of heart attack, atherosclerosis, and obesity. It also stabilises blood sugar levels, curbing appetite and potentially preventing hunger attacks.
9
Various benefits
1 people found this helpful
Inositol is beneficial for numerous conditions, from diabetic nerve pain to high cholesterol and even polycystic ovary syndrome. It's been shown to help balance chemicals, aiding conditions like panic disorders and potentially reducing the risk of heart attack through improved cholesterol levels.
9
ITPP enhances heart attack recovery
We explored the potential of myo-inositol trispyrophosphate (ITPP) as a treatment for heart attacks and its effect on heart tissue injured by low oxygen levels. This research indicates ITPP modifies hemoglobin in red blood cells, enhancing the delivery of oxygen throughout the body.
Using an animal model for myocardial infarction, we observed that ITPP administration provided significant protection against heart failure and aided in recovery from left ventricular remodeling following the heart attack.
In our laboratory studies, heart muscle cells exposed to low oxygen levels reacted quickly to ITPP treatment, showing increased activity of a protein known as HIF-1. Interestingly, this overactivity was countered by ITPP when it was in the red blood cells, which suggests a strong connection between shear stress from blood flow and oxygen release facilitated by the modified hemoglobin.
Overall, the findings indicate that ITPP could be a game-changer in treating injuries to heart tissues related to low oxygen or ischemia. This approach may open new avenues for effectively managing damage caused by heart attacks.
Using an animal model for myocardial infarction, we observed that ITPP administration provided significant protection against heart failure and aided in recovery from left ventricular remodeling following the heart attack.
In our laboratory studies, heart muscle cells exposed to low oxygen levels reacted quickly to ITPP treatment, showing increased activity of a protein known as HIF-1. Interestingly, this overactivity was countered by ITPP when it was in the red blood cells, which suggests a strong connection between shear stress from blood flow and oxygen release facilitated by the modified hemoglobin.
Overall, the findings indicate that ITPP could be a game-changer in treating injuries to heart tissues related to low oxygen or ischemia. This approach may open new avenues for effectively managing damage caused by heart attacks.
References
- Oknińska M, El-Hafny-Rahbi B, Paterek A, Mackiewicz U, Crola-Da Silva C, et al. Treatment of hypoxia-dependent cardiovascular diseases by myo-inositol trispyrophosphate (ITPP)-enhancement of oxygen delivery by red blood cells. J Cell Mol Med. 2020;24:2272. 10.1111/jcmm.14909
